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On the Right Track
Assisted living makes a move to Alzheimer's care

By Andrew MacPherson and Balaji Gandhi, Volpe Brown Whelan & Co.

Recent advances in medicine have greatly improved the treatment and management of physical ailments, such as cancer and heart disease. These advances boost the likelihood that people will live long enough to encounter the various mental disorders common in the elderly. As a result, mental conditions, such as Alzheimer's disease and related dementia (ARD), have rapidly increased their prevalence, making it hard for assisted living to resist coming aboard to offer ARD care.

These diseases affect a high percentage of the rapidly growing U.S. elderly population. In 1998, nearly 4.3 million people over the age of 65 suffered from Alzheimer's disease, according to Volpe Brown Whelan & Co. Including all other forms of dementia affecting the elderly, this population was more than six million, representing more than 17 percent of all Americans above the age of 65.

Alzheimer's disease dramatically increases in prevalence as people age beyond 65. Of people aged 65 to 75, 5 percent to 10 percent of the population have the disease.1 But, of people over the age of 85, nearly 50 percent have Alzheimer's disease.2

The growing demand for assisted-living services and the simultaneous boom in the demand for ARD care is being fueled by the growth of the population cohort aged 85 and older. Currently, there are approximately four million people over the age of 85 in the country. This cohort is projected to grow to 4.3 million in 2000 and 5.7 million by 2010. The U.S. Bureau of the Census is projecting an increase of 10.3 percent over the next three years and 46.8 percent over the next 13 years. In addition, this age group is projected to increase at a compound annual rate of 2.4 percent throughout the year 2030.

Family members spend an average of more than 100 hours per week caring for their loved ones. The increased demands on a caregiver's time frequently lead to difficulty sleeping and increased levels of depression. Past and current studies attempt to analyze the social and physical impact on family caregivers in different care settings (e.g., home health and adult day care).

As the severity of the disease increases, so do the associated costs. It is estimated that the total annual costs for the treatment of Alzheimer's disease exceeds $105 billion. In the late stages of the disease, the level of care required necessitates either full-time, in-home nursing or placement into an assisted-living or skilled-nursing facility. It is also estimated that in the severe stages of the disease, annual costs are $45,000 per patient.

Supply and Demand

The 4.3 million Americans with Alzheimer's in 1998 accounted for approximately 12.5 percent of the total population over 65. Currently, only 87,000 skilled-nursing beds and 30,000 assisted-living beds are specifically designated to care for these residents.

The majority of seniors with ARD are either in their homes or in skilled-nursing facilities due to a lack of options. In recent years, many skilled-nursing providers have designated a percentage of beds to special-care units (SCUs) to treat ARD. Projections have been made that the total number of SCUs and dementia-care assisted-living facilities cover only 3.5 of the total potential market population.

Despite the increase in the number of SCUs, several studies assessing them indicate that the type of care provided is not materially different from traditional skilled-nursing units. The existing Certificate of Need (CON) regulations, relating to SCUs as well as the consumer demand for an alternative setting of care specifically designed for ARD residents, will limit the expansion of dementia SCUs.

Although ARD have been clinically diagnosed conditions for nearly 100 years, most senior-care providers have only begun to develop discreet programs of care in the last several years. Even today, the majority of seniors with ARD are either cared for by family members full-time or are inappropriately placed into skilled-nursing facilities.

Assisted-living facilities have grown to fill the gap between skilled-nursing facilities on the higher end of the acuity scale, and independent living and home healthcare on the lower end. The recent rapid growth in assisted living is a result of the need for a cost-effective alternative to skilled-nursing care for individuals better suited to a residential rather than an institutional setting.

The programs of care and services at assisted-living facilities are designed to keep residents both physically and mentally active. Care programs in assisted-living facilities are generally designed to foster bonds between residents and their caregivers. Through their daily interaction in social activities and providing assistance with ADLs, trained caregivers are able to quickly identify any physical and psychological changes in residents. These same goals apply to ARD care. As a result, many of the programs and activities utilized in assisted-living facilities are easily adapted to caring for seniors with ARD. Therefore, several companies already providing higher acuity assisted-living services could, without undue effort, add programs to care for seniors with ARD.

Leading Programs of Care

The design and construction of Alzheimer's and dementia-care facilities have been greatly influenced by clinical research findings and the general increase in the public's awareness. Most design characteristics that are beneficial for Alzheimer's care are also beneficial for traditional assisted living. Therefore, purpose-built Alzheimer's facilities can easily be transformed to accommodate assisted-living residents, thereby all but nullifying the threat of functional obsolescence.

Several leading public and private assisted-living companies offer well-defined, dementia-care programs. In many cases, the care programs and facilities were designed to meet the recommendations made by the medical and social-services communities.

For example, in the public universe, Alterra (formerly Alternative Living Services Inc.), provides specialized dementia care to capture significant market share. As of March 31, the company operated more than 2,500 ARD units (15 percent of the company's total operating capacity) in its purpose-built Clare Bridge Memory Care Residences. The Clare Bridge program is designed to nurture independence, improve self-esteem and provide optimum comfort to each memory-impaired resident. The physical environment at each Clare Bridge facility allows residents to wander safely and engage in memory-enhancing activities in a homelike setting. Caregivers at these communities are assigned to specific residents to assist with ADLs.

In the private arena, Portland, Ore.-based Encore Senior Living, a provider of assisted-living-based, dementia-care services, operated nearly 1,045 ARD units as of June 1. Encore's ARD concept, Rediscovery™, represented more than 40 percent of the company's total operating units. Rediscovery specializes in later stages of Alzheimer's disease, offers several different facility-types and price points, and establishes a variety of research and advisory affiliations.

While many existing assisted-living providers implement dementia-care programs as a component of their overall package of services, several companies exclusively dedicated to ARD care also have been established. For example, Uncommon Care, based in Austin, Texas, currently operates four facilities in Texas. The company's prototype facility, Barton House, looks more like a home than a traditional nursing facility or hospital. Primrose Alzheimer's Living also operates assisted-living-style facilities focused exclusively on ARD, including the development of larger, multibuilding campuses as well as adult day-care services. Silverado Senior Living, of Aliso Viejo, Calif., operates specialty-care communities designed to meet ARD residents' physical and emotional needs, including family support. Silverado utilizes physicians, registered nurses, social workers and research professionals, together with family members, to identify and provide for the needs of each resident.

There are currently only a small number of assisted-living facilities, or wings of facilities, dedicated to caring for seniors with ARD. As more assisted-living-based ARD programs are established, more nursing-home residents requiring specialized care for these services will transfer into this more comforting, stimulating and homelike setting.

Andrew J. MacPherson is vice president and senior analyst at Volpe Brown Whelan & Co. (VBW). He joined VBW in 1998 as an analyst covering the assisted-living sector. Prior, Mr. MacPherson spent several years at Salomon Brothers as a junior analyst in equity research, covering the assisted-living sector and as a financial analyst in corporate finance in the firms' Health Care Group. Balaji Gandhi is an associate at VBW. Before joining VBW in 1998, he worked for HealthCare Financial Partners Inc. For more information, call (415) 274-4400.

Estimated Total Annual Healthcare Expenditures for Care and Treatment of Alzheimer's
1998 2000 2010 2020 %Change1998-2020
Population (000s)
65-74 18,365 18,136 21,057 31,385 70.9%
75-84 11,924 12,315 12,681 15,378 29.0
85+ 3,996 4,259 5,671 6,460 61.7
65+ 34,285 34,710 39,409 53,223 55.2
Individuals With AD (000s)
65-74 725 716 832 1,240 71.0
75-84 1,651 1,706 1,756 2,130 29.0
85+ 1,905 2,030 2,703 3,079 61.7
65+ 4,281 4,452 5,291 6,449 50.6
AD Cases by Level of Severity (000s)
Mild 1,927 2,003 2,381 2,902
Moderate 1,648 1,714 2,037 2,483
Severe 706 735 873 1.064
Estimated Annual Cost by Level of Severity
Mild $8,500 $8,843 $10,780 $13,141
Moderate 35,000 36,414 44,388 54,109
Severe 45,000 46,818 57,071 69,569
Implied Total Annual Costs (billions)
CAGR
Mild $16.4 $17.7 $25.7 $38.1 --
Moderate 57.7 62.4 90.4 134.3 --
Severe 31.8 34.4 49.8 74.0 --
Total Annual Costs $105.9 $114.5 $165.9 $246.4 3.9%
U.S. Bureau of the Census, Current Population Reports, 1997, and Evans, D.A., et al., "Estimated Prevalence of Alzheimer's Disease in the United States," Journal of the American Medical Association, 1990, (68) 267-289 and Volpe Brown Whelan & Co.
1U.S. Department of Health and Human Services, Agency for Health Care Policy Research, Early Alzheimer's Disease: Recognition and Assessment, September 1996.

2U.S. Department of Health and Human Resources, Alzheimer's Disease Fact Sheet, August 1995.


Breakthrough Vaccine Discovery Extends Hope to Alzheimer's Victims

By Wendi Hope King

Word has spread like wildfire about the possibility of a vaccine for Alzheimer's disease. A recent study published in the journal Nature, revealed a technique that may also possibly treat other neurological diseases, such as Parkinson's. San Francisco-based Elan Pharmaceuticals developed AN-1792, which seems to prevent and reduce the presence of proteins that cause Alzheimer's and other dementia. So far, only mice have been tested--but with success.

The two experiments used genetically engineered mice to study the drug's effects. The Alzheimer's Association reported that Elan's results showed that, in comparison to a control group, mice that were immunized at an age before protein development never developed any signs of Alzheimer's. In the second experiment, mice already showing signs of Alzheimer's pathology were treated with AN-1792, which halted and reduced the level of plaques.

Alzheimer's disease is caused by a protein (beta amyloid) that accumulates in the brain tissue, reported Dr. Dale Schenk, vice president of neurobiology at Elan Pharmaceuticals and the report's head author, in an online (abcnews.com) chat July 8. AN-1792 is a synthetic mimic of the plaque material that stimulates the immune system to attack and remove the plaque from the brain tissue, he continued. The drug attacks the deposits, but it is unsure if it will prevent them.

Although neurons cannot regenerate, recuperation is possible, and hopes are high for that effect after removing the cause of the problem. So far, there are no side effects, and it is too soon to tell if a person's mental status will improve.

Currently, Elan is examining four other possible treatments, although AN-1792 is the most advanced at this time. Predictions for when the drug will be available span between four and 10 years. The company has plans to file an application this year with the U.S. Food and Drug Administration to begin the clinical study of the drug on humans.

"Until now, we had no way of directly altering the Alzheimer's disease pathology," concluded Schenk. "This study--although in mice--suggests that the very real possibility now exists to potentially treat and possibly prevent Alzheimer's disease."

For more information, contact the Alzheimer's Association at (800) 272-3900; Web www.alz.org

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